The Elbow

Intra-articular injections

Mode of Action

Corticosteroids injected locally have a local anti-inflammatory effect
with, as a consequence, suppression of swelling, effusion and pain.

This is caused by reducing the number of leucocytes at the inflammatory
site as well as their activity.
The latter is through a stabilization of the lysosomal membrane with, as a
consequence, decreased liberation of cytotoxic enzymes.

They also reduce the escape of plasma protein across the capillary
membrane, so decreasing both oedema formation and the release of
neuro transmitters.